You should not use Provigil For those who have at any time experienced an allergic reaction or pores and skin rash even though using modafinil or armodafinil (Nuvigil).
Coadministration of encorafenib with sensitive CYP3A4 substrates may lead to improved toxicity or decreased efficacy of such agents.
Evaluation Modafinil : an evaluation of its use in too much sleepiness connected to obstructive rest apnoea/hypopnoea syndrome and change perform sleep dysfunction.
modafinil will raise the amount or effect of mavacamten by impacting hepatic enzyme CYP2C19 metabolism. Contraindicated. Strong or average CYP2C19 inhibitors may possibly improve mavacamten systemic publicity, causing coronary heart failure due to systolic dysfunction.
Provigil is used to treat excessive sleepiness because of slumber apnea, narcolepsy, or shift function rest dysfunction.
Repeated administration of modafinil for off-label use, including enhanced alertness and cognitive-boosting consequences in slumber deprivation, can lead to drug tolerance, which suggests the efficiency with the drug may possibly lessen as time passes.
Pediatric Use: Effectiveness and protection in pediatric people more information are usually not established. Modafinil isn't FDA-accepted for use in the pediatric population for just about any indication.
100mg Modafinil: A little more powerful than 75mg Armodafinil for many cause, Regardless that each are “50 percent” doses. eight+ hours of solid cognitive enhancement. Great when you need to obtain to snooze prior to midnight, but nevertheless really need to get sh*t done. Minor to no slight Unwanted effects.
Keep an eye on Closely (1)modafinil will increase the stage or effect of flibanserin by impacting hepatic enzyme CYP2C19 metabolism.
Pregnancy: It is classified as pregnancy classification C medicine by FDA. There is not any evidence to advise or exclude harm to your human fetus connected with modafinil.
Stiripentol is actually a CYP3A4 inhibitor and inducer. Keep track of CYP3A4 substrates coadministered with stiripentol for increased or lowered effects. CYP3A4 substrates may well demand dosage adjustment.
Allergy symptoms Tell your medical doctor Should you have at any time had any uncommon or allergic response to this drugs or any other medicines.
This medication is offered only with the health care provider's prescription. This products is available in the subsequent dosage forms:
While modafinil is utilised as a cognitive enhancer or "sensible drug" among healthful people today searching for enhanced concentrate and productiveness,[fourteen][15] its use exterior professional medical supervision raises considerations pertaining to possible misuse or abuse.